Pediatric tumours: liver tumours

نویسنده

  • Alexander J Towbin
چکیده

Pediatric liver tumors account for approximately 1% of all liver tumors and up to 2% of all pediatric malignancies [1,2]. While the overall incidence of liver tumors is rare, the liver remains the third most common organ of origin for solid abdominal tumors in the pediatric population [3]. The majority of pediatric liver tumors, both benign and malignant, occur (almost) exclusively in children. Benign tumors account for one-third of all pediatric hepatic neoplasms and include infantile hepatic hemangioma, focal nodular hyperplasia, mesenchymal hamartoma, and hepatic adenoma [2-5]. Malignant neoplasms account for the remaining two-thirds of pediatric liver tumors. The most common malignancies are hepatoblastoma, hepatocellular carcinoma, fibrolamellar hepatocellular carcinoma, undifferentiated embryonal sarcoma, and biliary rhabdomyosarcoma [4-6]. While the majority of these tumors are unique to children, focal nodular hyperplasia, hepatocellular adenomas, and hepatocellular carcinoma have counterparts in adults. The presentation, risk factors, and imaging appearance of these overlapping tumors differs in the pediatric population as compared to adults [7,8]. Even though there are a number of different liver tumors, the radiologist can often make a confident diagnosis based on the clinical information and imaging appearance of the mass [9,10]. The purpose of this lecture is to describe the imaging work-up for pediatric liver masses and then discuss each tumor, focusing on its unique clinical and imaging features.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Appendicular Neuroendocrine Tumours in Children: Unicentric Retrospective Study

Background: Neuroendocrine Neoplasms (NEN) represent 60% of all appendicular tumours. This type of cancer is predominantly benign.  In this study, appendicular NEN tumours in children were investigated. Materials and Methods: This retrospective study was conducted on 540 patients underwent emergency appendectomy for the treatment of clinically suspected appendicitis at the department of p...

متن کامل

Renal Tumours in Adults with Correlation between Fuhrman Grading and Proliferative Marker

Background: Definite data regarding the incidence and distribution of renal tumours in eastern India is not known. For better management, as it is essential to identify patients with poor prognosis, prognostic factors like stage, nuclear grade and their relationship to molecular markers are also unclear in this region. The purpose of our study was to assess the spectrum of adu...

متن کامل

Radiotherapy techniques for intracranial tumours

ABSTRACTIntracranial tumours often require radiotherapeutic approaches that differ from other sites. Their specific requirements merit a specialized discussion. A brief review of radiotherapy techniques to treat intracranial tumours is presented with emphasis on the author’s own experience and work, where appropriate. A clinical introduction is presented first followed by a description of bot...

متن کامل

Evaluation of the prognostic value of CD117 and CK20 biomarkers in urinary bladder carcinoma

Background: Over-expression of CD117 and cytokeratin 20 (CK20) is seen in many malignancies. Given that few studies have been conducted regarding the role of these biomarkers in the etiology of bladder tumours, this study aimed to evaluate the prognostic value of CD117 and CK 20 biomarkers in the benign and malignant tumours of urinary bladder carcinoma. Methods: This case-control study was co...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2014